Table 3.
Immunohistologic EMB Analysis of Intramyocardial Infiltration in GCM Patients Based on Conventional Histology or on Gene Profiling.
| Patient Data | IGCM (By Histology) |
IGCM (By Gene Profiling) |
|---|---|---|
| Immunohistology | ||
| - CD3+ lymphocytes infiltration/mm2 | 312.4 ± 297.3 | 125.8 ± 196.3 * |
| - LFA-1+ lymphocytes infiltration/mm2 | 462.6 ± 413.8 | 183.4 ± 215.0 * |
| - CD45R0+ T memory cell infiltration/mm2 | 533.3 ± 349.6 | 114.9 ± 502.3 * |
| - perforin+ cell infiltration/mm2 | 16.23 ± 26.00 | 14.14 ± 32.23 |
| - Mac-1+ macrophages infiltration/mm2 | 428.8 ± 344.0 | 181.1 ± 227.1 * |
Note: Immunohistologic marker: CD3 = T-lymphocytes; LFA-1 = leukocyte function antigen-1; Mac-1 = macrophage-1 antigen; CD45R0 (UCHL1) = leucocyte common antigen; perforin = cytotoxic cells. The data are presented as mean ± standard deviation. Asterisk (*) indicates significant variance between the incidence of IGCM derived from histology and that derived from gene profiling.