Table 3.
General linear multivariate models exploring interaction between gender and other clinical determinants in key variables with prognostic value in HF with reduced ejection fraction patients, over KCCQ global summary score.
| Women | Men | p Value | |
|---|---|---|---|
| LVEF >30% | 56.0 ± 1.5 | 63.3 ± 1.0 | <0.001 |
| LVEF <30% | 52.8 ± 2.1 | 61.3 ± 1.4 | 0.003 |
| p value for interaction | 0.669 * | ||
| Age <75 years | 56.1 ± 1.8 | 64.2 ± 1.0 | <0.001 |
| Age >75 years | 53.0 ± 1.7 | 60.3 ± 1.3 | 0.001 |
| p value for interaction | 0.766 * | ||
| NYHA I-II | 66.2 ± 1.8 | 72.7 ± 1.1 | 0.003 |
| NYHA III-IV | 42.1 ± 1.8 | 51.2 ± 1.2 | <0.001 |
| p value for interaction | 0.364 * | ||
| Comorbidities number <5 | 54.9 ± 1.8 | 64.4 ± 1.3 | <0.001 |
| Comorbidities number >5 | 55.3 ± 2.0 | 61.0 ± 1.2 | 0.005 |
| p value for interaction | 0.193 * | ||
| Ischemic etiology: yes | 55.3 ± 1.5 | 62.9 ± 1.3 | <0.001 |
| Ischemic etiology: no | 54.5 ± 2.1 | 62.3 ± 1.0 | <0.001 |
| p value for interaction | 0.959 * | ||
| Recent admission: yes | 58.3 ± 1.8 | 66.2 ± 1.1 | <0.001 |
| Recent admission: no | 51.4 ± 1.7 | 59.0 ± 1.2 | <0.001 |
| p value for interaction | 0.902 * | ||
LVEF: Left ventricular ejection fraction, NYHA: New York Heart Association functional class. Recent admission was defined as admission for heart failure within the last 6 months. * p-value of interaction between gender and variable.