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The overall dose-response effect of HCTZ use on NMSC in the CDM network for “Ever use”. Each analysis was tested for heterogeneity (“Test*” indicates Cochran’s Q and I2 value tests). In the significant associations, the chi-square tests for heterogeneity in most cases were insignificant and its I2 values were almost zero. These suggest that there was little between-study variability in the found associations.
