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. 2020 Aug 25;9(9):2740. doi: 10.3390/jcm9092740

Table 2.

Clinical monitoring of VHL patients with retinal HBs receiving propranolol in an off-label treatment: previous lesions, dosage, and response to the treatment.

Case Gender, Age Lesions Prior to Propranolol Treatment Propranolol Treatment Initiation
(months)
Propranolol Treatment Doses (mg/kg/day) Response to Propranolol Treatment
1 Female, 32 Bilateral retinal HB January 2017
(36 months)
Started at 0.66 and increased to 1.5 No lesions detected along the treatment
2 Male, 24 Medulla HB extracted and partial nephrectomy due to ccRCC left renal lesions May 2018
(22 months)
Started at 0.66 and increased to 1.2 Stable bilateral cystic lesions after starting treatment
3 Male, 28 Left eye retinal HB, multiple tumoral and cystic lesions August 2016
(47 months)
Started at 0.5 and increased to 1.4 Stable bilateral lesions but one after starting treatment
4 Male, 22 Right eye retinal HB and extracted cerebellum HB April 2018
(16 months)
1.8 Stable 3 bilateral cystic lesions after starting treatment