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. 2020 Jun 30;8(3):348. doi: 10.3390/vaccines8030348

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Frequency and proportion of MBC responders in retrospective cohorts. (A) Frequency of HPV-16- (left panel) and HPV-18-specific (right panel) specific memory B cells (MBCs) per millions of total IgG-secreting B cells. (B) Proportion of MBC responders to HPV-16- (left panel) and HPV-18- (right panel) defined as subjects with detectable (>455 cell/million of total IgG-secreting B cells) or L-18 (>450 cell/million of total IgG-secreting B cells) HPV type-specific memory B cells in retrospective cohort with 2 or 3 doses of prior 4vHPV vaccination.