Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Global root-mean-square-deviation (RMSD), a metric for large-scale conformational changes of SIM1 variants versus WT. Global root-mean-square-deviation for each variant is given, where every residue from the protein is averaged into an accumulated measure of the total amount of change of the structure as a function of time. Colors are given in the figure legend.
