Table 6.
Clinical studies carried out for tissue healing with different LIPUS therapies. (LIPUS parameters 30–100 mW/cm2, frequency 1.5 MHz, 1 kHz, duty cycle of 20%).
| NCT Number | Conditions | Interventions | Outcome |
|---|---|---|---|
| NCT00423956 | Root resorption | LIPUS | Induced inflammatory root resorption |
| NCT00744861 | Lumbar degenerative disc disease | LIPUS | Posterolateral fusion success |
| NCT00931749 | Knee osteoarthritis | LIPUS | Knee cartilage thickness and volume |
| NCT01623804 | Knee osteoarthritis | LIPUS | Pain and physical function |
| NCT02253212 | Glioblastoma | LIPUS + Drug | Blood–brain barrier opening |
| NCT02034409 | Osteoarthritis | LIPUS | Symptoms reduction |
| NCT02383160 | Fractures | LIPUS | Time to union of scaphoid non-unions |
| NCT00667849 | Tibial fractures | LIPUS | Healing of tibial fractures |
| NCT02872922 | Diabetes mellitus | LIPUS | Changes arterial endothelial function |
| NCT03251807 | Malocclusion | LIPUS | Dentoskeletal changes |
| NCT03119961 | Brain diseases | LIPUS | Blood–brain barrier opening |
| NCT03347084 | Brain diseases | LIFUP | Improvements in cognitive functioning |
| NCT03329482 | Low back pain | LIPUS | Pain intensity of patients |
| NCT03744026 | Glioblastoma | LIPUS + Drug | Blood–brain barrier opening |
| NCT03679507 | Osteoarthritis in the knee | LIPUS | Pain intensity measure |
| NCT03657056 | Temporal lobe epilepsy | LIFUP | Changes of the blood-oxygenation level |
| NCT03717922 | Brain diseases | LIFUP | Auditory verbal learning |
| NCT04021420 | Metastatic melanoma | LIPUS + Drug | Blood–brain barrier opening |
| NCT04131387 | Female stress urinary incontinence | LIPUS | Urinary incontinence questionaire |
| NCT03868293 | Drug resistant epilepsy | FOCCUS LIPUS | Reducing seizure frequency |
| NCT04406337 | Osteoarthritis | LIPUS | Visual analog scale (Pain) |
| NCT04339972 | Healthy adults | LIFUP | Analgesia |
LIFUP: Low-Intensity Focus Ultrasound Pulsation.