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Crude incidences of invasive meningococcal disease in children 0–5 years of age pre and post introduction of 4CMenB in Tuscany (A) or Veneto (B). In Tuscany, 3 out of 4 cases of Invasive Meningococcal Disease (IMD) and in Veneto 5 out of 7 cases of IMD in the post-4CMenB era occurred in not-vaccinated children. Abbreviations: MenB: Neisseria meningitides serogroup B; 4CMenB = multicomponent meningococcal serogroup B vaccine.
