Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic overview of the exotic CAR formats used in clinical trials treating solid tumors. The number of clinical trials using a specific CAR format is indicated. Data was extracted from clinicaltrials.gov. TM = transmembrane domain, PD1 = programmed cell death protein 1, IL13 (E13Y) = mutated IL-13 optimized to bind IL-13Rα2, TE1 = promiscuous ErbB ligand derived from EGF and TGFα. The Motifolio Scientific Illustration Toolkit was used for the generation of parts of this figure.
