Table 1.
Clinical characteristics of the 82 patients.
| Patient Characteristics | |
|---|---|
| Age at the first diagnosis of melanoma | years |
| Median | 57 (46–67) |
| Range | 17–85 |
| Sex | no of patients (%) |
| Female | 37(45) |
| Male | 45 (55) |
| Melanoma type | no. of patients (%) |
| Cutaneous | 42 (51) |
| Acral | 14 (17) |
| Uveal | 8 (10) |
| Mucosal | 9 (11) |
| Occult | 9 (11) |
| Tumor thickness of primary melanoma | mm |
| Median (IQR) | 3.3 (1.8–5.1) |
| Range | 0.38–5.1 |
| The tumor stage at the time of tumor sequencing | no. of patients (%) |
| Stage II | 5 (6) |
| Stage IV | 77 (94) |
| Immunotherapy | 76/82 (93) |
| Targeted therapy | 21 (26) |
| Chemotherapy | 4 (5) |
| No systemic treatment | 5 (6) |
| Origin of the tissue sequenced | no of patients (%) |
| Lymph node | 19 (23) |
| Other metastasis | 57 (70) |
| Primary melanoma | 6 (7) |
| Pretreatment of tissue sequenced | no. of patients (%) |
| Tissue therapy naïve | 52 (63) |
| Tissue progressive under ICI | 18 (22) |
| Tissue progressive under targeted therapy | 8 (10) |
| Tissue progressive under chemotherapy | 4 (5) |