ACAN |
aggrecan |
ADAMTS |
a disintegrin and metalloproteinase with thrombospondin motif |
ALPL |
alkaline phosphatase |
AP-1 |
activator protein 1 |
ATF2 |
activating transcription factor 2 |
ATG |
autophagy-related |
BAPX-1 |
homeobox protein Nkx-3.2 |
C/EBP |
CCAAT-enhancer-binding protein |
COL10A1 |
collagen type X |
COL2A1 |
collagen type II |
CREB |
cAMP response element binding protein |
DMM |
destabilization of the medial meniscus |
ECM |
extracellular matrix |
ENaC |
epithelial sodium channel |
ETS |
erythroblast transformation specific |
FOXA |
forkhead box transcription factor class A |
FOXO |
forkhead box transcription factor class O |
GATA4 |
GATA-binding factor 4 |
GLI |
glioma-associated oncogene |
HAT |
histone acetyltransferase |
HDAC |
histone deacetylase |
HIF |
hypoxia-inducible factor |
IHH |
Indian hedgehog |
IKK |
IκB kinase |
IL |
interleukin |
KCa |
Ca2+ activated potassium channels |
LC3 |
light chain 3 |
MAPK |
mitogen-activated protein kinase |
MEF2C |
myocyte-specific enhancer factor 2C |
MMP |
matrix matalloproteinase |
MR |
master regulator |
mTOR |
mechanistic target of rapamycin kinase |
MYOD |
myoblast determination protein |
NFAT |
nuclear factor of activated T-cell |
NFκB |
nuclear factor kappa B |
OA |
osteoarthritis |
PAX |
paired box |
PI3K |
phosphatidylinositol 3-kinase |
PITX1 |
paired-like homeodomain 1 |
PKA |
cAMP-dependent protein kinase A |
PTHrP |
parathyroid hormone-like protein |
RUNX2 |
runt-related transcription factor 2 |
SASP |
Senescence-associated secretory phenotype |
siRNA |
small interfering RNA |
SIRT1 |
sirtuin 1 |
SMAD3 |
SMAD family member 3 |
SOX9 |
SRY-BOX transcription factor 9 |
SP1 |
specificity protein 1 |
STAT3 |
signal transducer and activator of transcription 3 |
T3 |
active thyroid hormone |
TASK-2 |
Acid-sensing potassium channel |
tBHP |
tert-butyl-hydroperoxide |
TCF/LEF |
T-cell factor/lymphoid enhancer factor |
TF |
transcription factor |
TFD ODN |
transcription factor decoy oligodeoxynucleotides |
TFEB |
transcription factor EB |
TGFβ |
transforming growth factor β |
TMEM16 |
Ca2+ activated chloride channel |
TNFα |
tumor necrosis factor alpha |
TSS |
transcription start site |
ULK1/2 |
unc-51-like autophagy activating kinase 1 and 2 |
ZKSCAN3 |
zinc-finger protein with KRAB and SCAN domain 3 |