Table 4.

Bleeding Academic Research Consortium (BARC) standardized definitions developed mainly for cardiovascular trials.

BARC Definitions
Type 0	No bleeding
Type 1	Bleeding that is not actionable and does not cause the patient to seek unscheduled intervention.
Type 2	Any overt, actionable sign of hemorrhage requiring non-surgical medical intervention by a healthcare professional.
Type 3	a	Overt bleeding plus hemoglobin drop of 3 to <5 g/dL (provided hemoglobin drop is related to bleed)
	b	Overt bleeding plus hemoglobin drop ≥5 g/dL (provided hemoglobin drop is related to bleed) Cardiac tamponade Bleeding requiring surgical intervention for control or intravenous vasoactive agents
	c	Intracranial hemorrhage confirmed by autopsy or imaging or lumbar puncture Intraocular bleed compromising vision
Type 4	CABG-related or perioperative intracranial bleeding within 48 h
Type 5	a	Probable fatal bleeding
	b	Definite fatal bleeding