Table 1.
Clinical manifestations of infectious mononucleosis in children of different ages.
| Clinical manifestations | Total(n = 61) | 1–3 years(n = 23) | 4–6 years(n = 23) | 7–14 years(n = 15) | P |
|---|---|---|---|---|---|
| Fever | 60 (98.4) | 23 (100.0) | 23 (100.0) | 14 (93.3) | 0.246b |
| Nasal obstruction | 30 (49.2) | 16 (65.2) | 10 (43.5) | 4 (26.7) | 0.028a |
| Sleep snoring | 6 (9.8) | 5 (21.7) | 1 (4.3) | 0 (0.0) | 0.078b |
| Sniffles | 15 (24.5) | 6 (26.1) | 6 (26.1) | 3 (20.0) | 0.893a |
| Cough | 39 (63.9) | 15 (65.2) | 17 (73.9) | 7 (46.7) | 0.229a |
| Pharyngalgia | 21 (34.4) | 3 (13.0) | 8 (34.8) | 10 (66.7) | 0.003a |
| Headache | 5 (8.2) | 0 (0.0) | 2 (8.7) | 3 (20.0) | 0.061b |
| Fatigue | 12 (19.7) | 0 (0.0) | 5 (21.7) | 7 (46.7) | 0.001b |
| Abdominal pain | 2 (3.3) | 2 (8.7) | 0 (0.0) | 0 (0.0) | 0.334b |
| Vomiting | 6 (9.8) | 3 (13.0) | 1 (4.4) | 2 (13.3) | 0.637b |
| Diarrhea | 1 (1.6) | 0 (0.0) | 1 (4.3) | 0 (0.0) | 1.000b |
| Arthralgia | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | – |
| Eyelid edema | 25 (41.0) | 9 (39.1) | 10 (43.5) | 6 (40.0) | 0.952a |
| Rash | 13 (21.3) | 7 (30.4) | 2 (8.7) | 4 (26.7) | 0.182b |
| Hepatomegaly | 23 (37.7) | 8 (34.8) | 11 (47.8) | 4 (26.7) | 0.394a |
| Splenomegaly | 26 (42.6) | 7 (30.4) | 9 (39.1) | 10 (66.7) | 0.080a |
| Jaundice | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | – |
| Cervical lymphadenopathy | 60 (98.4) | 22 (95.6) | 23 (100.0) | 15 (100.0) | 1.000b |
| Axillary and inguinal lymphadenopathy | 29 (47.5) | 8 (34.8) | 9 (39.1) | 12 (80.0) | 0.014a |
| Enlarged tonsils | 61 (100.0) | 23 (100.0) | 23 (100.0) | 15 (100.0) | – |
| Tonsillar exudation | 51 (83.6) | 18 (78.3) | 20 (86.9) | 13 (86.7) | 0.750b |
| Maximum body temperature (°C) | 29.2 (38.7, 39.6) | 39.5 (38.7, 39.9) | 39.0 (38.5, 39.3) | 39.0 (38.9, 39.1) | 0.193c |
| Fever duration (days) | 4.0 (3.0, 5.0) | 3.0 (2.0, 4.0) | 4.0 (2.0, 6.0) | 3.0 (1.0, 5.0) | 0.277c |
| Duration of tonsillar exudate absorption (days) | 5.0 (3.0, 5.0) | 5.0 (2.0, 5.0) | 5.0 (2.0, 5.0) | 5.0 (4.0, 5.0) | 0.822c |
| Length of hospital stay (days) | – | 10.87 ± 2.87 | 10.96 ± 3.08 | 10.67 ± 3.81 | 0.963d |
Notes: aχ2 test; bFisher’s exact test; cKruskal–Wallis test; danalysis of variance. Data are presented as number of patients (%), X ± S or median (interquartile range).