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. 2020 Sep 3;12(9):2492. doi: 10.3390/cancers12092492

Figure 5.

Figure 5

Correlation of mTOR pathway markers and metabolic enzymes (determined by IHC) with subtype distribution in breast cancer. H-scores for LDHA, CPT1A and FASN showed significant correlation with hormone receptor status (HR+ or HR-). LDHA H-scores increased from luminal A (LumA) to triple-negative breast cancer (TNBC) and, conversely, FASN H-scores decreased from LumA to TNBC (** p < 0.01, * p < 0.05, statistically significant). Ranges with median values are shown; bare circles represent outlier breast cancer cases.