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Effect of ONC206 in combination with paclitaxel on uterine serous cancer cell viability. ARK1, ARK2 and HEC50 cells were treated with ONC206 alone (0–10 μM) or in combination with paclitaxel (0–25 nM) for 72 h. ONC206 synergized with paclitaxel in reducing cell viability of USC cells. Three independent experiments were performed (mean ± standard deviation). The combination index was calculated using CompuSyn (combination index <1 indicates a synergistic effect).
