Table 3.
Distribution of genotypes of GSTM1 and GSTT1 among healthy controls and patients with larynx or hypopharynx cancer (Pearson χ2 test).
| Genotype | Healthy Controls (n = 23) n (%) | Larynx/Hypopharynx (80) n (%) |
OR (95% CI) | p-Value | Larynx Cancer (n = 75) n (%) | OR (85% CI) | p-Value | Hypopharynx Cancer (n = 5) n (%) |
OR (95% CI) | p-Value |
|---|---|---|---|---|---|---|---|---|---|---|
| GSTM1 | 2.83 (1.01–7.92) | 0.042 | 2.75 (0.98–7.76) | 0.049 | 4.25 (0.56–31.93) | 0.141 | ||||
| Absence or null | 6 (26.09) | 40 (50.00) | 37 (49.33) | 3 (60.00) | ||||||
| Presence | 17 (73.91) | 40 (50.00) | 38 (50.67) | 2 (40.00) | ||||||
| GSTT1 | 5.07 (1.71–15.04) | 0.002 | 4.71 (1.58–14.01) | 0.003 | 1.64 (1.18–2.28) | 0.090 | ||||
| Absence or null | 14 (60.86) | 71 (88.75) | 66 (88.00) | 5 (100.00) | ||||||
| Presence | 9 (39.14) | 9 (11.25) | 9 (12.00) | 0 (0) |