Table 1.
Characteristics of PCD patients aged 0–19 years with a definite PCD diagnosis (n = 476).
| Characteristic | N (%) | Age at Diagnosis (in Years) |
N (%) of Patients Diagnosed at 0–12 m |
|---|---|---|---|
| Median (IQR) | |||
| Total | 476 (100) | 3.36 (0.69–7.76) | 144 (30.3) |
| Sex | |||
| Male | 262 (55.0) | 2.62 (0.61–7.06) | 87 (33.2) |
| Female | 214 (45.0) | 4.38 (0.97–8.34) | 57 (26.6) |
| Country of residence | |||
| Argentina | 30 (6.3) | 1.5 (0.50–5.00) | 10 (33.3) |
| Australia | 19 (4.0) | 1.26 (0.40–3.78) | 9 (47.4) |
| Colombia | 11 (2.3) | 6.61 (4.04–8.34) | 1 (9.1) |
| Cyprus | 5 (1.0) | 0.61 (0.21–0.67) | 4 (80.0) |
| Czech Republic | 21 (4.4) | 4.75 (1.49–9.28) | 4 (19.0) |
| Italy | 89 (18.7) | 1.62 (0.38–5.67) | 36 (40.4) |
| Norway | 25 (5.3) | 0.63 (0.10–7.17) | 14 (56.0) |
| Turkey | 31 (6.5) | 10.11 (7.37–12.53) | 0 (0.0) |
| United Kingdom | 245 (51.5) | 3.53 (0.89–8.08) | 66 (26.9) |
| NRD | |||
| No | 193 (40.6) | 4.96 (1.10–8.44) | 43 (22.3) |
| Yes | 261 (54.8) | 1.96 (0.50–6.40) | 98 (37.5) |
| No information | 22 (4.6) | 2.47 (1.42–9.40) | 3 (13.6) |
| Organ laterality | |||
| Situs solitus | 218 (45.8) | 5.93 (2.00–9.08) | 37(17.0) |
| Laterality defect | 240 (50.4) | 1.44 (0.42–5.07) | 103 (42.9) |
| No information | 18 (3.8) | 6.35 (1.09–9.54) | 4 (22.2) |
| Clinical characteristics groups | |||
| No NRD, situs solitus | 114 (24.0) | 6.47 (2.73–9.08) | 15 (13.2) |
| NRD, situs solitus | 132 (27.7) | 5.44 (1.50–9.41) | 27 (20.5) |
| No NRD, laterality defect | 91 (19.1) | 2.51 (0.67–6.97) | 30 (33.0) |
| NRD, laterality defect | 139 (29.2) | 0.91 (0.31–3.17) | 72 (52.0) |
PCD: primary ciliary dyskinesia, NRD: neonatal respiratory distress, IQR: interquartile range.