Skip to main content
. 2020 Jan 27;10(9):1669–1679. doi: 10.1016/j.apsb.2020.01.014

Figure 4.

Figure 4

PROTAC 9c is efficacious in tumor xenograft models of PC-3 cells. (A) Effect of PROTAC 9c on tumor growth in vivo. Tumor growth was monitored over time. (B) Tumors were harvested for analysis of the differences in tumor size. (C) Scatter plot of the tumor mass. (D) Body weights of mice in the antitumor study against PC-3 cells. (E) Immunohistochemical staining of tumor tissue samples from the vehicle group and experimental group. (F) Effects on morphologic changes in tumor tissue samples, HE staining of tumor tissue samples from the vehicle group and experimental group. Data are means ± SEM, n = 5, ∗∗P < 0.01.