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. 2020 Sep 9;9(9):2061. doi: 10.3390/cells9092061

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Mechanism of RNA interference (RNAi) and options for therapeutic intervention. (1) Substitution of tumor suppressor micro-RNA (miRNA, miR) in form of pre-miRNA or miRNA mimics, thereby inducing RNAi. (2) Blocking of oncogenic miRNA by miRNA-specific antagomirs (anti-miR). This figure is reprinted with permission from [103]. Copyright © 2020; John Wiley and Sons.