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. 2019 Dec 18;10(9):1694–1708. doi: 10.1016/j.apsb.2019.12.011

Figure 5.

Figure 5

The accumulation of ginsenosides in plasma, tumor tissues, and endothelial cells after multiple administration of SMI to Balb/c nude mice harboring LoVo xenograft. (A) The constituent ratio–time profiles of ginsenosides in plasma and tumors after single or multiple (8-day) administration of SMI (10 mL/kg/day). (B) The constituent ratio of ginsenosides in SMI, plasma, tumor, and endothelial cell measured 20 min after 15-day SMI treatment. The ratio changes of different types of ginsenosides are separated by red dotted lines in the graph. Data were expressed as mean ± SEM. PPD: protopanaxadiol-type ginsenosides; PPT: protopanaxatriol-type ginsenosides.