Table 3.
HA and neuraminidase (NA) strain identification and sequence coverage in IIVs based on LC-MS/MS assay.
| Protein | Coverage, % | |||||
|---|---|---|---|---|---|---|
| U3 | U4 | SGU | SGF | GP | VG | |
| HA A/Brisbane/02/2018 | 31.4 | 34.3 | 12.0 | 32.0 | 5.5 | 28.3 |
| HA A/Kansas/14/2017 | 46.5 | 50.0 | 16.0 | 33.7 | 12.2 | 37.5 |
| HA B/Colorado/06/2017 | 37.2 | 44.9 | 19.0 | 42.2 | 11.7 | 29.2 |
| HA B/Phuket/3073/2013 | - | 47.8 | - | - | - | - |
| NA A/Brisbane/02/2018 | 22.8 | 20.7 | 8.0 | 18.8 | 6.2 | 18.1 |
| NA A/Kansas/14/2017 | 40.7 | 37.1 | 11.0 | 27.7 | 10.2 | 33.3 |
| NA B/Colorado/06/2017 | 35.4 | 21.9 | 9.0 | 27.5 | 5.6 | 26.4 |
| NA B/Phuket/3073/2013 | - | 25.5 | - | - | - | - |
Note: Coverage (%) is the percentage of peptide coverage of theoretically predicted amino acid sequences of proteins identified via MS/MS.