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. 2020 Aug 31;9(9):2819. doi: 10.3390/jcm9092819

Table 3.

FOT values of enrolled subjects with COPD.

Hypercapnia Normocapnia p Value
(n = 22) (n = 102)
R5, cmH2O/L/s
Whole breath 5.05 (3.58–6.43) 3.50 (2.72–4.32) 0.001
Inspiratory 5.56 (3.62–7.75) 3.91 (3.00–5.02) 0.004
Exspiratory 4.32 (3.28–5.07) 3.09 (2.34–3.83) 0.005
delta R5 1.17 (0.25–2.07) 0.77 (0.47–1.29) 0.001
R20, cmH2O/L/s
Whole breath 2.78 (2.01–3.77) 2.56 (2.21–3.31) 0.891
Inspiratory −1.47 (−3.45–0.22) 2.87 (2.33–3.62) <0.001
Exspiratory 3.94 (1.87–7.51) 2.34 (1.90–3.06) 0.009
delta R20 −5.46 (−11.25–−0.21) 0.41 (0.22–0.75) <0.001
R5–R20, cmH2O/L/s
Whole breath 9.29 (2.54–18.76) 0.80 (0.53–1.19) <0.001
Inspiratory −14.75 (−30.01–−1.01) 1.00 (0.66–1.47) <0.001
Exspiratory 24.04 (3.71–48.77) 0.57 (0.34–0.89) <0.001
delta (R5-R20) −38.78 (−78.77–−2.98) 0.38 (0.18–0.58) <0.001
X5, cmH2O/L/s
Whole breath −2.66 (−4.51–−1.12) −0.74 (−1.90–−0.37) <0.001
Inspiratory −3.34 (−5.26–−1.09) −0.78 (−2.41–−0.35) <0.001
Exspiratory −1.96 (−3.01–−1.16) −0.74 (−1.34–−0.39) <0.001
delta X5 −0.79 (−2.29–0.09) −0.09 (−0.96–0.18) 0.108
Fres, Hz
Whole breath 19.03 (11.99–22.57) 9.90 (7.44–15.05) <0.001
Inspiratory 20.87 (12.16–23.89) 10.47 (7.46–16.73) <0.001
Exspiratory 16.76 (11.66–22.18) 9.81 (7.34–13.04) <0.001
delta Fres 2.34 (0.89–4.35) 1.18 (−0.62–4.14) 0.431
ALX, cmH2O/L/s Hz
Whole breath 22.70 (5.17–36.94) 2.91 (1.24–12.16) <0.001
Inspiratory 29.53 (5.20–47.61) 2.98 (1.12–16.00) <0.001
Exspiratory 14.31 (5.75–23.49) 2.92 (1.28–7.25) <0.001
delta ALX 7.76 (0.81–18.79) 0.74 (−0.47–7.24) 0.059