Table 2.
The enzymatic inhibitory activity, expressed as IC50 of the Leucosidea sericea total extract (LSTE), the intact fractions (F1 and F2), and those of their corresponding silver nanoparticles (LSTE-, F1- and F2-AgNPs) using two assays (µg/mL).
| Items | Alpha-Amylase (IC50) (µg/mL) | Alpha-Glucosidase (IC50) (µg/mL) |
|---|---|---|
| LSTE | 3.50 ± 0.70 a | 8.10 ± 0.60 a |
| LSTE-AgNPs | 14.92 ± 1.0 b | 21.48 ± 0.90 b |
| F1 | NA | 7.30 ± 0.50 a |
| F1-AgNPs | 13.24 ± 0.60 b | 18.76 ± 1.00 c |
| F2 | 18.9 ± 0.20 c | 7.10 ± 0.40 a |
| F2-AgNPs | 19.13 ± 0.80 c | 8.75 ± 0.70 a |
| Acarbose | 10.20 ± 0.40 d | 61.00 ± 1.50 d |
The results are expressed as mean ± SD of three different independent experiments (n = 3). Results not sharing a common superscript alphabet (a–d) are significantly different (p < 0.01). Acarbose (standard), NA (not active at the tested concentrations).