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. 2020 Sep 22;9(9):3054. doi: 10.3390/jcm9093054

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Changes of circulating levels of glucose (top panel), insulin (middle panel), and glucagon (bottom panel) in obese adolescents after a fixed-dose lunch (completely consumed within 15 min starting at T75) administered with amino acid mix (L-arginine, L-leucine, L-glutamine, and L-tryptophan) or placebo (maltodextrins) at T0. See the text for further details. Values are expressed as means ± SDs. The number of subjects was 14. * p < 0.05 vs. the corresponding T0 value; × p < 0.05 vs. the value in the maltodextrin-treated group at the corresponding time point. A two-way ANOVA with repeated measures (with the two factors time and group and the interaction time × group) followed by the post hoc Tukey’s test was used.