FIGURE 4.

B3GNT5 is highly expressed in GBM. A, The comparison of B3GNT5 expression by GBM grade using REMBRANDT RNAseq dataset. Data are means ± SEM (nontumor, n = 28; astrocytoma, n = 147; oligodendroglioma, n = 67; GBM, n = 219; Grade I and II, n = 100; Grade III, n = 85; Grade IV, n = 130). ^*** P < .001. B, Kaplan‐Meier survival curves of 181 GBM patients (B3GNT5 high, n = 91; B3GNT5 low, n = 90, P < .0001) in the REMBRANDT microarray dataset. C, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis for upregulated genes related to high expression of B3GNT5 in the REMBRANDT microarray dataset