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. 2020 Sep 3;10(3):113. doi: 10.3390/jpm10030113
FP Fluoropyrimidines
DPD Dihydropyrimidine Dehydrogenase
DPYD-PGx DPYD-Pharmacogenomics
PCR Polymerase Chain Reaction
5-FU 5-Fluorouracil
ADR Adverse Drug Reaction
HFS Hand-Foot Syndrome
SNPs Single-Nucleotide Polymorphisms
CPIC The Clinical Pharmacogenetics Implementation Consortium
DPWG Dutch Pharmacogenetics Working Group
DPYD-AS DPYD-Activity Score
TDM Therapeutic Drug Monitoring
MTHFR Methylene-Tetrahydrofolate Reductase
TYMS-TSER Thymidylate Synthase-Thymidylate Synthase Enhancer Region
GSTP1 Glutathione S-Trasferase-p1
UH2/U ratio Dihydrouracil/Uracil Ratio
CTC-AE Common Terminology Criteria for Adverse Events
RECIST Response Evaluation Criteria in Solid Tumours
HPLC High-Performance Liquid Chromatography
UHPLC-MS/MS Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry
MeSH Medical Subject Heading
PRISMA Preferred Reporting Items for Systematic reviews and Meta-Analyses
FOLFOX 5-FU, Leucovorin and Oxaliplatin
CT scan Computed Tomography Scan
FOLFIRI 5-FU, Leucovorin and Irinotecan
PRAC Pharmacovigilance Risk Assessment Committee
EMA European Medicines Agency
CHMP Committee for Medicinal Products for Human Use
AUC Area Under the Curve
LC-MS/MS Liquid Chromatography-Tandem Mass Spectrometry
PBMCs Peripheral Blood Mononuclear Cells