| FP | Fluoropyrimidines |
| DPD | Dihydropyrimidine Dehydrogenase |
| DPYD-PGx | DPYD-Pharmacogenomics |
| PCR | Polymerase Chain Reaction |
| 5-FU | 5-Fluorouracil |
| ADR | Adverse Drug Reaction |
| HFS | Hand-Foot Syndrome |
| SNPs | Single-Nucleotide Polymorphisms |
| CPIC | The Clinical Pharmacogenetics Implementation Consortium |
| DPWG | Dutch Pharmacogenetics Working Group |
| DPYD-AS | DPYD-Activity Score |
| TDM | Therapeutic Drug Monitoring |
| MTHFR | Methylene-Tetrahydrofolate Reductase |
| TYMS-TSER | Thymidylate Synthase-Thymidylate Synthase Enhancer Region |
| GSTP1 | Glutathione S-Trasferase-p1 |
| UH2/U ratio | Dihydrouracil/Uracil Ratio |
| CTC-AE | Common Terminology Criteria for Adverse Events |
| RECIST | Response Evaluation Criteria in Solid Tumours |
| HPLC | High-Performance Liquid Chromatography |
| UHPLC-MS/MS | Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry |
| MeSH | Medical Subject Heading |
| PRISMA | Preferred Reporting Items for Systematic reviews and Meta-Analyses |
| FOLFOX | 5-FU, Leucovorin and Oxaliplatin |
| CT scan | Computed Tomography Scan |
| FOLFIRI | 5-FU, Leucovorin and Irinotecan |
| PRAC | Pharmacovigilance Risk Assessment Committee |
| EMA | European Medicines Agency |
| CHMP | Committee for Medicinal Products for Human Use |
| AUC | Area Under the Curve |
| LC-MS/MS | Liquid Chromatography-Tandem Mass Spectrometry |
| PBMCs | Peripheral Blood Mononuclear Cells |