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. 2020 Aug 24;12(9):2389. doi: 10.3390/cancers12092389

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Kaplan–Meier analysis demonstrating the association between multi-agent chemotherapy use and OS in the overall cohort (A), in patients with large (>5 cm) tumors (B), with prior radiation (C), treated at high-volume centers (D), and in patients with primary high-grade extremity and trunk STS who had large (>5 cm) tumors and were treated with radiation at high-volume centers (E). Study sample derived from the NCDB from 2004 to 2016. NCDB = National Cancer Database; OS = overall survival; STS = soft tissue sarcoma.