Table 4.

Anticancer effect of silibinin nanoparticles in in vitro and in vivo studies.

Nanomaterial Type	Cancer Type/Effect	Study Type	Reference
PVA-Eudragit	ORAL CARCINOMA inhibition of apoptosis KB cells	In vitro model	Gohulkumar M. et al., 2014 [67]
PEG	BREAST CANCER cytotoxic effect on MCF 10A	In vitro model	Sajjadiyan S. Z. et al., 2016 [68]
AEAA-PEG-PCL	BREAST CANCER 4T1 cells angiogenesis suppression	Animal model (mice)	Jiang M. et al., 2020 [71]
PTX-SB-Dex-DOCA	LUNG CANCER inhibition of tumour growth A549 cells	Animal model (mice)	Huo M. et al. 2020 [70]
S/C-pW nanoparrticles	BREAST CANCER anti-metastasis activity	Animal model (mice)	Liu Y. et al., 2020 [72]