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Schematic representation of polyunsaturated fatty acid (PUFA) generation in C. elegans. (A) Model of generation of PUFAs under normal conditions in N2 (WT) with the intact enzymatic machinery, where LA and ALA act as precursors for generation of PUFAs (AA and EPA). (B) Model of novel PUFA synthesis in fat-3(wa22) mutants, where ALA acts as the precursor for synthesis of JuA.
