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. 2020 Aug 25;12(9):2406. doi: 10.3390/cancers12092406

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Classification of long non-coding RNAs (lncRNAs) based on their genomic location. Intergenic lncRNA is located between two protein-coding genes. Intronic lncRNA lies entirely within the intron of a protein-coding gene. Sense lncRNA is transcribed from the same strand and in the same direction as the nearby protein-coding genes. Antisense lncRNA is transcribed from an opposite strand. Bidirectional lncRNA is located within 1 kb of the promoter region of a protein-coding gene but is transcribed from an opposite strand.