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. 2020 Aug 26;10(9):1241. doi: 10.3390/biom10091241

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Intramuscular content of different components of sphingolipid pathway in rats after chronic cannabidiol (CBD) treatment, i.e., (A) sphinganine (SFA), (B) sphinganine-1-phosphate (SFA1P), (C) ceramide (CER), (D) sphingosine (SFO), (E) sphingosine-1-phosphate (S1P), and (F) sphingosine-1-phosphate/ceramide ratio (S1P/CER Ratio) in the red gastrocnemius muscle of rats fed a standard diet (control group) or high-fat diet (HFD). The data are expressed as mean values ± SD, n = 10 in each group. ^a p < 0.05 significant difference: control group vs. examined group; ^b p < 0.05 significant difference: HFD vs. HFD + CBD.