Figure 1.

Counseling process at the high-risk clinic of gastrointestinal cancer for diagnosis of GC or PC familial or hereditary syndromes. In the high-risk clinic for gastrointestinal cancer, all patients with GC or PC were evaluated at a young age (≤60) or at any age if they also had another tumor; healthy individuals who had a family history of one of these malignancies were also evaluated. After counseling and molecular or genetic analyzes if it was indicated, all families were classified as a form of hereditary, familial or sporadic cancer. GC, gastric cancer; PC, pancreatic cancer; IHC-MMR, Immunohistochemical analysis of DNA repair proteins.