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. 2020 Aug 21;9(9):1930. doi: 10.3390/cells9091930

Figure 8.

Figure 8

Effect of the selective ER-α agonist and antagonist on the migration of GBM cells. (A) U251 and (B) U87 cells that were treated for 20 h, with PPT (10 nM, selective ER-α agonist), MPP (1 μM, selective ER-α antagonist), PPT + MPP, and vehicle (V, DMSO 0.01%). Wound healing assays determined the migratory capacity of the U251 and U87 cells. Representative images show wound closure at 0, 10, and 20 h and quantification of the wound area. Results are expressed as the mean ± standard error of the mean (SEM); n = 3; * p < 0.05 vs. all other groups.