Skip to main content
. 2020 Aug 12;8(3):451. doi: 10.3390/vaccines8030451

Table 2.

TBEV proteins eliciting TBEV-specific immune responses in humans upon TBEV infection or TBEV vaccination.

Infection Vaccination
Protective antibodies E [88,93]
NS1 [94,95,96,97]		 E [88,93]
NS1 [97] #†
CD4+ T cells C [98,99,100]
E [98,99,100]
NS1 [101]		 C [98,99,100]
E [98,99,100,102]
CD8+ T cells * NS2A [103]
NS3 [103,104]
NS4B [103]
NS5 [103]		 -

†: protective potential was shown in mouse models only [97,101,105,106,107,108]. #: presence of NS1-specific antibodies in vaccinees still under discussion [94,95,96,97]. *: CD8+ T cell epitopes were identified for TBE patients with HLA-A2 and HLA-B7 haplotypes [103,104].