Table 3.

Immunological responses and inflammation.

Patients Treated in Chronic HIV-1 Infection
Cell mediated immune responses
Slightly higher CD4+ LPR in patients with lower VL No relation in magnitude and breadth of CD8+ T cell responses with VL	Garcia [4]
Inverse correlation between CD4+ LPR and VL	Kilby [5]
Positive correlation of both, CD4+ LPR and CD8+ breadth responses, with time off ART	Lévy [6]
Inverse correlation between CD4+ LPR and CD8+ magnitude and breadth and VL	Andrés [7]
No association between CD4+ and CD8+ responses and longer TtR	Angel [9]
No association of CD4+ LPR with time off ART	Pialoux [10]
No association of T cell responses and VL	Mothe B [11]
High CD4+ responses but absence of CD8+ responses associated to higher VL and shorter time to restart ART	Papagno [13]
Patients Treated During Acute HIV-1 Infection
No association between CD4+ and CD8+ responses and time off ART	Goujard [8]
HIV antibodies
No association of NAb (pre-ATI) with VL set point	Li [14]
anti-C5/gp41 increase from week 1-preATI associated with low VL	Huang [15]
Inflammation markers
VL control associated with increase in TNFα and IL-6 from week 1-preATI	Huang [16]
Higher VL associated with increase in CRP from week 1-preATI	Huang [15]

Note: LPR: lymphoproliferative responses; VL: viral load; ART: antiretroviral therapy; NAb: neutralizing antibodies; ATI: analytical treatment interruption; TNFα: tumor necrosis factor alpha; CRP: c-reactive protein.