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. 2020 Aug 28;12(9):2446. doi: 10.3390/cancers12092446

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Correlations between cytokine levels and % of JAK2V617F-mutated alleles. Analysis of the cytokine levels and %JAK2V617F of the 55 patients with JAK2V617F-mutated MPN, using Spearman’s t-test, revealed positive correlations between %JAK2V617F and IP-10 (a) and IL-1Rα (b), and a negative correlation between leptin and %JAK2V617F, in PV only (c). (d–f) Positive correlations in PV only between the %JAK2V617F and IP-10 (d), IL-1Rα (e) and IL-1β (f). (g) Positive correlation between IL-33 and %JAK2V617F in ET only.