Table 1.
Main characteristics of Electrochemotherapy (ECT), Gene Electrotransfer (GET) and Irreversible Electroporation (IRE).
| ECT | GET | IRE | |
|---|---|---|---|
| Spares non-dividing cells | yes | yes | no |
| Drugs used | bleomycin or cisplatin | plasmids | none |
| Electrical parameters | 8 × 1000 V/cm 100 µs | varies | 80–90 × 1000–30,000 V/cm 100 µs |
| Thermal effect | no | no | depends on the protocol |
| Regular use in human medicine | yes | no | yes |
| Regular use in veterinary medicine | yes | no | no |
| Uses | cancer | cancer, vaccines, gene therapy | cancer, ablation of tissues (cardiac) |