Table 1.
Clinical characteristics of the 23 children with SARS-CoV-2 infection.
| Clinical Characteristics | Total n = 23 |
<2 Years Old n = 14 (61%) |
2–10 Years Old n = 2 (9%) |
>10 Years Old n = 7 (30%) |
|---|---|---|---|---|
| Age: years; mean [range] | 4.9 [0.1; 17.6] | 0.4 [0.1; 1.2] | 5.2 [4.5; 6.0] | 14.0 [11.4; 17.6] |
| Gender: boys, n (%) | 13 (57%) | 9 (64%) | 1 (50%) | 3 (43%) |
| Ancestry, n (%) | ||||
| Asia | 1 (4%) | 1 (7%) | 0 (0%) | 0 (0%) |
| Europe | 8 (35%) | 5 (36%) | 1 (50%) | 2 (29%) |
| Middle East and Maghreb | 4 (17%) | 3 (21%) | 0 (0%) | 1 (14%) |
| Sub-Saharan Africa/Caribbean | 10 (43%) | 5 (36%) | 1 (50%) | 4 (57%) |
| Comorbidities, n (%) | 12 (52%) | 5 (36%) | 1 (50%) | 6 (86%) |
| Asthma | 3 (13%) | 2 (14%) | 0 (0%) | 1 (14%) |
| Sickle cell disease | 3 (13%) | 1 (7%) | 0 (0%) | 2 (29%) |
| Overweight/obesity | 3 (13%) | 0 (0%) | 1 (50%) | 2 (29%) |
| Other | 4 (17%) | 1 (7%) immune deficiency 1 (7%) premature birth |
1 (14%) myoclonic-astatic epilepsy 1 (14%) Bronchiectasis 1 (14 %) COPD |
|
| Exposure to SARS-CoV-2, n (%) | ||||
| Family cluster | 20 (87%) | 14 (100%) | 1 (50%) | 5 (71%) |
| Other exposure | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Unknown | 3 (13%) | 0 (0%) | 1 (50%) | 2 (29%) |
| Initial symptoms, n (%) | 21 (91%) | 13 (93%) | 1 (50%) | 7 (100%) |
| Fever | 18 (78%) | 11 (79%) | 1 (50%) | 6 (86%) |
| Fatigue/deterioration of general status | 12 (52%) | 8 (57%) | 1 (50%) | 3 (43%) |
| Cough | 11 (48%) | 7 (50%) | 0 (0%) | 4 (57%) |
| Pharyngitis (sore throat) | 4 (17%) | 1 (7%) | 1 (50%) | 2 (29%) |
| Dyspnea | 5 (22%) | 2 (14%) | 0 (0%) | 3 (43%) |
| Wheezing | 4 (17%) | 2 (14%) | 0 (0%) | 2 (29%) |
| Acute rhinitis | 11 (48%) | 9 (64%) | 1 (50%) | 1 (14%) |
| Acute anosmia/ageusia | 1 (4%) | 0 (0%) | 0 (0%) | 1 (14%) |
| Myalgia/arthralgia | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Nausea or vomiting | 3 (13%) | 0 (0%) | 1 (50%) | 2 (29%) |
| Diarrhea | 4 (17%) | 1 (7%) | 1 (50%) | 2 (29%) |
| Abdominal pain | 5 (22%) | 0 (0%) | 2 (100%) | 3 (43%) |
| Abnormal cry | 4 (17%) | 4 (29%) moaning | 0 (0%) | 0 (0%) |
| Abnormal skin color | 6 (26%) | 4 (29%) mottled skin | 1 (50%) diffuse rash | 1 (14%) thoracic rash |
| Neurological signs | 5 (22%) | 3 (21%) hypotonia | 1 (50%) drowsiness | 1 (14%) drowsiness |
| Initial vital signs, median [range] | ||||
| Temperature (°C) | 37.9 [36.6; 39.9] | 38.0 [36.6; 38.7] | 36.7 [36.6; 36.7] | 38.1 [36.9; 39.9] |
| Respiratory rate (/min) | 40 [15; 60] | 46 [24; 60] | 18 [18; 18] | 30 [15; 60] |
| Oxygen saturation (%) | 98 [85; 100] | 99 [96; 100] | 99.5 [99; 100] | 97 [85; 99] |
| Cardiac rate (/min) | 144 [64; 195] | 161 [126; 195] | 113.5 [106; 121] | 123 [64; 155] |
Abbreviations: COPD: chronic obstructive pulmonary disease. Sub-section headings are indicated in bold.