Table 1.
Recent studies analyzing the redox status of (in)fertile people during assisted reproductive technologies (ART) cycles.
| Cell Type | ASSAY | Method | Results | Ref. |
|---|---|---|---|---|
| Sperm | ORP | MiOXSYS | Higher values in infertile men | [116] |
| SDF | Halosperm | [117] | ||
| Sperm | ORP | MiOXSYS | Higher values in infertile men | [118] |
| Sperm | GSH/GSSG | enzymatic | Altered in varicocele and leukocytospermia | [119] |
| Catalase | [120] | |||
| Sperm | GSH-Px | enzymatic | Correlate with sperm parameters | [121] |
| Follicular fluid | HPSC | Levels of estradiol and progesterone are related to the redox status | [122] | |
| Embryo | General Redox species | luminol | No association presence of ROS in culture media with embryo quality | [123] |
| Serum samples endometriosis |
GSH/GSSG MDA TAC 8OHdG |
Oxidative stress markers were good predictors of clinical pregnancy and live births after ICSI in women with stage I or II endometriosis. | [124] | |
| Blood and Follicular fluid | ROS TAC |
Flow cytometry Fluorometric assay |
Oxidative stress markers were good predictors of ART outcomes. | [125] |
ORP: oxidation–reduction potential; SDF: sperm DNA fragmentation; MDA: malondialdehyde; GSH/GSSG: Glutathione-disulphide glutathione; TAC: total antioxidant capacity; 8OHdG: 8-hydroxy-2’-deoxyguanosine; HPSC: hydrogen peroxide scavenging capacity.