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. 2020 Jun 29;8(3):346. doi: 10.3390/vaccines8030346

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Schematic representation of BTV-4 Morocco, a bluetongue virus (BTV) strain generated as a consequence of a reassortment event between BTV-4 and BTV-1 serotypes. Three concentric protein layers constituted by VP2 and VP5 (outer capsid), VP7 (intermediate layer) and VP3 (subcore), are depicted. Structural proteins VP1, VP4 and VP6 are located inside the inner capsid constituting the RNA polymerase complex. Double-strand RNA segments 1 (VP1), 4 (VP4), 5 (NS1), 7 (VP7), 9 (VP6 and NS4) and 10 (NS3/NS3A and NS5), deriving from BTV-1, are represented in red. Double-strand RNA segments 2 (VP2), 3 (VP3), 6 (VP5) and 8 (NS2), deriving from BTV-4, are colored green. BTV dsRNA segment 5, encoding for NS1, is striped.