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. 2020 Aug 26;8(3):475. doi: 10.3390/vaccines8030475

Figure 2.

Figure 2

Antibody (immunoglobulin G1, or IgG1) response to recombinant IrSPI (A) and IrLip1 (B) in vaccinated mice. Antibody titers were determined by ELISA in serum samples collected at different time points from day 0 to day 90 against the specific protein both in vaccinated mice (solid lines) and control mice (dashed lines) that received only adjuvant. Arrows indicate dates for 1st, 2nd, and 3rd immunizations (days 0, 14, and 28) and tick infestations (Day 42). Antibody titers are represented as arbitrary units.