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Loss of ARID1A expression among human IPMN is mostly restricted to low-grade gastric subtype IPMN. (A) Quantification of IHC staining for ARID1A on patient samples representing IPMNs of various subtypes and dysplasia grade revealed lost expression specifically in low-grade lesions of gastric subtype. (B) IHC staining for ARID1A in gastric versus intestinal subtype of human IPMN and in high-grade versus low-grade dysplasia in the same patient (C). Scale bar is 100 µm.
