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. 2020 Sep 15;9(9):2981. doi: 10.3390/jcm9092981

Table 5.

Summary of available literature. DY, diagnostic yield; n/s, not specified.

Authors, Year Country Type of Study No. Of Patients (M/F) Age:
Mean ±SD
Or
Median (Range in Years)
Type of Endoscope Caecal Intubation Rate,
n (%)
Time to Caecum:
Mean ±SD
Or Median (Range in Min)
DY Of BAC (n) Interventions Performed (n) Adverse Events, (n)
May et al., 2006 [13] Germany Prospective,
Single Centre
14 (6/8) 62 ± 15 Single Balloon 14/14 (100) n/s Polyps (6)
IBD (3)
Cancer (2)
Polypectomy (6)
Biopsy (5)
Polypectomy Bleeding (1)
Kaltenbach et al., 2006 [14] USA Prospective,
Single Centre
20 (16/4)
66 ± 12 Single Balloon 19/20 (95) 28 ± 20 Significant (7)
(Polyps (5)
Ibd (2))
Polypectomy (5)
Biopsy (1)
None
Das 2007 [15] USA n/s,
Single Centre
16 (n/s) n/s Double Balloon 14/16 (87.5) 27 ± 9.5 n/s Polypectomy (6)
Haemostasis (1)
None
Gay & Delvaux, 2007 [16] France Retrospective,
Single Centre
29 (5/24) 54±17 Double Balloon 28/29 (96.6) 18 ± 14 Diverticulosis (7)
Polyps (4)
IBD (2)
Biopsy (8)
APC (2)
Polypectomy (2)
None
Moönkemuüller et al., 2007 [17] Germany n/s,
Single Centre
7 (3/4) 64(50–75) Double Balloon 7/7 (100)
15 (9–25) Diverticulosis (2)
Polyps (2)
Stenosis (2)
n/s n/s
Pasha et al., 2007 [18] USA Retrospective,
Single Centre
16 (5/11) 69 ± 12 Double Balloon 14/16 (87.5) 27 ± 9.5 n/S Polypectomy (6)
APC (1)
n/s
Moreels & Pelckmans, 2008 [19] Belgium Retrospective,
Single Centre
26 (n/s) n/s Double Balloon 23/26 (89) n/s n/S n/s n/s
Moreels et al. 2010 [20] Belgium Prospective,
Single Centre
45 (28/17) 63 ± 2 Double Balloon 42/45 (93.3) n/s Polyps (18) Polypectomy (18)
APC (3),
Biopsy (2)
None
Teshima et al., 2010 [10] Netherlands Prospective,
Single Centre
23 (14/8) 53(19–75) Single Balloon 22/23 (96) 30 (20–60) Polyps (6)
IBD (5)
Diverticulosis (2)
Polypectomy (6)
Dilation (1)
None
Matsushita et al., 2011 [21] Japan Retrospective,
Single Centre
24 (n/s) n/s Double Balloon 24/24 (100) 17 n/S 17 Interventions (n/s) n/s
Keswani et al., 2011 [22] USA Prospective,
Single Centre
14 (4/10) 58.5 ± 12.5 (35–74) Single Balloon 13/14 (92.9) 22 ± 18 (10–81) Polyps (7) n/s None
Dzeletovic et al., 2012 [23] USA Retrospective,
Single Centre
53 (12/41) 71(43–83) Single Balloon& Double Balloon 51/53 (96) (26/26 SBC, 25/27 DBC) 19 (7–58) Polyps (32)
Diverticulosis (21)
Polypectomy (37) None
Goómez et al., 2012 [24] USA Retrospective,
Single Centre
45 (21/24) 67(21–84) Double Balloon 46/51 (90) n/s Polyps (28)
Angiectasia (5)
Polypectomy (28) None
Hotta et al., 2012 [25] Japan Prospective,
Multicentre
110 (62/48) 66.5(27–79) Double Balloon 110/110 (100) 12 (4–47) Polyps (55)
Cancer (5)
Polypectomy (45)
Biopsy (8)
Mild Mucosal Injury (1)
Suzuki et al., 2012 [26] Japan Prospective,
Single Centre
47 (22/25) 63.4 ± 10.9 Double Balloon 47/47 (100) 13.0 ± 5.3 Polyps (21)
C
ancer (1)
Polypectomy/Resection (6)
Further Surgery (1)
None
Kobayashi et al., 2013 [27] Japan n/sSingle Centre 15 (8/7) 65.7 ± 8.7 (38–81) Single Balloon 15/15 (100) 22.9 ± 8.9 (9–40) Polyps Radiation Colitis (3)
Diverticulosis (3)
Polypectomy (N/S)
Biopsy (N/S)
None
Yamada et al., 2013 [28] Japan Prospective,
Single Centre
21 (n/s) 71.5 ± 7.8 Single Balloon& Double Balloon 20/21 (95) 12.8 (9.5–42) Polyps (8)
Diverticulosis (7)
Cancer (1)
Polypectomy (8)
Biopsy (1)
None
Becx & Al-Toma, 2014 [29] Netherlands Retrospective,
Single Centre
114 (45/69) 64.8(31–91) Double Balloon 101/114 (88.6) n/s New Diagnoses (55) Polypectomy (51)
Further Surgery (7)
Bleeding with Spontaneous Resolution (2)
Nemoto et al., 2014 [30] Japan Prospective,
Single Centre
28 (14/14) 74(35–88) Double Balloon 28/28 (100) 16 (6–66) n/S n/s None
Yung et al., 2016 [11] UK Retrospective,
Single Centre
57 (26/31) 62.9(20–89) Double Balloon 55/57 (96.5) n/s 29 Polypectomy/APC (22) None
Sulz et al., 2016 [31] Switzerland Retrospective,
Single Centre
100 (46/54) 70(38–87) Single Balloon 98/100 (98) 27.5 (4–92) Diverticulosis (54)
Polyps (47),
Colitis (4)
Cancer (1)
Polypectomy (45)
APC (1)
Mucosal Defect After Polypectomy (1)
Haematochezia (1)
Despott et al., 2017 [32] UK Prospective,
Single Centre
22 (7/15) 68 ± 10 Double Balloon 22/22 (100) 17.5 (16.0–23.7) n/S n/s n/s
Hermans et al., 2018 [33] Netherlands Retrospective,
Single Centre
61 (34/27) 65(29–82) Double Balloon 60/63 (95) n/s Polyps (34)
Cancer (3)
Polypectomy (34)
Biopsy (3)
Bleeding at Polypectomy (1)
Robertson et al., 2020 UK/Sweden Retrospective,
Multicentre
122 (56/66) 64.4 ± 12.3 Single Balloon& Double Balloon 113/122 (92.6) 20.9 ± 13.5 Polyps (67)
, Cancer (4)
Colitis (13),
Diverticulosis (11)
Angiectasia (5)
Polypectomy (60)
APC (4)
Biopsy
Vasovagal Reaction During Polypectomy (1)