Table 1.

Iohexol plasma clearance in the one (CL1; CL1f) and two-compartment models (CL2). SM = simplified method based on CL2. CL1f: CL1 with the adjustment formula. MAPE = mean absolute percentage error.

Sheep	Gender	Weight (kg)	CL2	CL1	CL1f	CL SM	MAPE CL2 vs. CL1f	MAPE SM vs. CL2
1	F	56	125	135	121	130	3.1	3.3
2	F	49	111	128	116	116	4.2	5.1
3	F	52	171	208	174	170	1.5	0.5
4	F	48	79	89	84	75	5.7	5.0
5	F	40	92	101	94	90	1.8	2.3
6	F	51	99	112	103	96	3.8	3.6
7	F	45	106	120	109	102	3.0	3.7
8	M	45	98	110	101	97	3.2	0.9
9	M	49	101	111	102	97	0.9	4.6
10	M	67	171	194	164	174	4	1.5
11	M	54	117	121	110	115	6	2.2
12	M	65	119	132	119	120	0.2	1.0
13	M	49	100	106	98	99	2.2	1.9
14	M	51	116	130	117	114	1.0	1.6
15	M	104	167	189	161	165	3.7	1.1