. Author manuscript; available in PMC: 2020 Oct 16.

Published in final edited form as: Pract Radiat Oncol. 2019 Jul 29;10(1):e16–e26. doi: 10.1016/j.prro.2019.07.010

Table 3.

Grade 4 lymphopenia risk and survival estimates according to nomogram risk groups.

			Progression-free survival				Overall survival
Nomogram risk group (sum score)	n (% of total)	G4 lymphopenia (%)^†	Median (months)	5-year (%)	HR (95% CI)	p value	Median (months)	5-year (%)	HR (95% CI)	p value
Low risk (<12)	221 (25.7)	10.0	70.3	53.5	Ref	-	78.3	54.9	Ref	-
Low-intermediate risk (12–13)	154 (17.9)	24.0	NR	50.2	1.06 (0.77–1.46)	0.720	59.9	48.6	1.18 (0.86–1.62)	0.296
High-intermediate risk (13–15)	288 (33.5)	43.4	28.5	40.9	1.37 (1.05–1.78)	0.019^*	44.8	43.7	1.39 (1.07–1.80)	0.015^*
High risk (>15)	197 (22.9)	70.1	19.4	39.9	1.68 (1.28–2.20)	<0.001^*	34.7	36.8	1.57 (1.19–2.08)	0.002^*

: Statistically significant (p<0.05).

^†

: Observed probability of grade 4 lymphopenia.

CI: Confidence interval. G4: Grade 4. HR: Hazard ratio. NR: Not reached.