TABLE 3.

Dosage and common adverse drug reactions of integrase strand transfer inhibitors available in southern Africa.

Drug	Recommended dosage	Common or severe ADR
RAL	400 mg 12 hourly	Headache and other CNS side effects, gastrointestinal upset, hepatitis and rash (rare), rhabdomyolysis (rare). Weight gain.
DTG	50 mg daily	Insomnia, headache and other CNS side effects, gastrointestinal upset, hepatitis and rash (rare). Possibly teratogenic. Weight gain.

ADR, adverse drug reaction; CNS, central nervous system; DTG, dolutegravir; RAL, raltegravir.