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. 2020 Sep 16;21(1):1115. doi: 10.4102/sajhivmed.v21i1.1115

TABLE 10.

Recommendations for resistance testing.

Regimen DTG-based therapy NNRTI-based therapy PI-based therapy
First-line regimen Recommended if the patient has been on regimen for > 2 years Not routinely recommended Not routinely recommended (rare scenario)
Second-line regimen Recommended if the patient has been on regimen for > 2 years Recommended (rare scenario) Recommended if the patient has been on regimen for > 2 years

DTG, dolutegravir; NNRTI, non-nucleoside reverse transcriptase inhibitor; PI, protease inhibitor.