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Recommended second-line regimen in patients who have failed a first-line regimen of two nucleoside reverse transcriptase inhibitors + dolutegravir.
| Failing first-line regimen | Advised second-line regimen |
|---|---|
| Two NRTIs + DTG | Only switch to second-line regimen if the resistance test shows DTG resistance and the second line should be two NRTIs (selected based on resistance test) + DRV/r |
DTG, dolutegravir; NRTI, nucleoside reverse transcriptase inhibitor; DRV, darunavir/ritonavir.
