Table 3.
Overlap between transcriptomic studies on the SN from PD patients.
| GSE7621 | GSE42966 | GSE49036 | GSE20164 | GSE54282 | GSE20163 | GSE20333 | Our Data | |
|---|---|---|---|---|---|---|---|---|
| DEGs | 932 | 64 | 872 | 242 | 24 | 432 | 133 | 304 |
| Overlap | 223 (24%) | 18 (28%) | 229 (26%) | 77 (32%) | 2 (8%) | 114 (26%) | 19 (14%) | 72 (24%) |
| Same direction | 206 (92%) | 14 (78%) | 218 (95%) | 71 (92%) | 1 (50%) | 103 (90%) | 12 (63%) | 66 (92%) |
The table includes the accession numbers of the studies used, the number of differentially expressed genes with p-value < 0.01 and log2FC < −0.5849 or log2FC > −0.5849 (DEGs), the number of DEGs overlapping between all studies (overlap), and the number of overlapping DEGs that are either upregulated or downregulated in the same direction in all studies where they appear as DEGs. Percentages of overlapping genes from the total DEGs, and percentages of overlapping genes in the same direction from the total number of overlapping genes, can be found between brackets in the rows “Overlap” and “Same direction”, respectively.