APC	antigen-presenting cell;
Cat	cathepsin;
CatB	cathepsin B;
CatK	cathepsin K;
CatL	cathepsin L;
CatS	cathepsin S;
CCL2	CC-chemokine ligand-2;
CD206	cluster of differentiation 206;
COX2	cyclooxygenase 2;
DC	dendritic cell;
EC	endothelial cell;
ECM	extracellular matrix;
EPR	enhanced permeability and retention;
FDA	Food and Drug Administration;
HPMA	poly(2-hydroxypropyl methacrylamide);
IL-6	interleukin 6;
JAM-B	junctional adhesion molecule B;
LE	ligand efficiency;
LHVS	leucine homophenylalanine vinyl sulfone;
MC38	murine colon adenocarcinoma;
MCF7	Michigan Cancer Foundation–7;
MDSC	myeloid-derived suppressor cell;
MHC	major histocompatibility complex;
MMR	mannose receptor;
MRI	magnetic resonance imaging;
PDB	protein database;
PEG	polyethylene glycol;
PLGA	PEG-block-poly-lactic-co-glycolic acid;
rhBMP-2	recombinant human bone morphogenetic protein-2;
SAR	structure–activity relationship;
siRNA	small interfering RNA;
TAM	tumor-associated macrophages;
TME	tumor microenvironment;
Treg	regulatory T cell;
ZINC	ZINC is not commercial;